This learning resource focuses on the harmful effects of three toxic substances—Lead, Formaldehyde, and Nickel—on lung health. It includes a series of activities aimed at understanding how these chemicals, commonly found in vaping aerosols, affect lung tissue and function. Activity 1 encourages students to research each toxic substance, detailing their specific impacts, such as inflammation from Lead, cancer risks from Formaldehyde, and allergic reactions caused by Nickel. Activity 2 involves synthesizing findings into a summary, while Activity 3 promotes discussion about the dangers of these chemicals for growing bodies through a think-pair-share format. Finally, Activity 4 challenges students to predict the long-term effects of prolonged exposure to these substances on lung health, enhancing their critical thinking skills regarding health choices related to vaping.