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This resource provides an in-depth lesson on fecal transplants and their role in curing patients infected with harmful bacteria. The lesson includes a scientific context from the Microbiome Research Institute, where students analyze data about a patient who underwent a fecal transplant. It explores key concepts such as the human microbiome, the impact of antibiotics, and how healthy gut bacteria can outcompete harmful bacteria. Students are guided through discussions, analysis of evidence, and reasoning related to the effectiveness of fecal transplants. The resource aims to equip students with the skills to write scientific arguments while addressing an important medical topic related to microbiomes and health.