Mutations: How Changes in DNA Affect Traits - Biology Reading Comprehension Worksheet

Help your students uncover the fascinating world of genetic mutations with this engaging reading comprehension worksheet! This resource provides an in-depth look at how changes in DNA—whether through point mutations, frameshift mutations, or environmental factors—can affect traits, lead to genetic disorders, or even contribute to evolutionary advantages. With real-world examples, including a case study on cystic fibrosis, students will develop a deeper understanding of how mutations shape life at the molecular level.

What’s Included:

• A detailed reading passage (~1,200 words) on the types, causes, and effects of genetic mutations.
• A case study on cystic fibrosis that illustrates how a mutation in the CFTR gene leads to this genetic disorder.
• Multiple-choice, matching, fill-in-the-blank, and short-answer questions designed to reinforce comprehension and critical thinking.
• A complete teacher answer key for quick and easy grading.
• Structured reading, keeps the focus on text-based learning and analysis.

Why This Resource is Perfect for Your Classroom:
This worksheet is an excellent tool for reinforcing key concepts about DNA, genetics, and mutations. Use it as a resource for deeper learning, sub plans, or in-class assignments. It aligns with Common Core standards and encourages students to apply their knowledge to real-world genetic examples, making it an essential part of any biology curriculum.

Learning Objectives:

• Understand different types of mutations and their effects on proteins.
• Analyze how mutations can lead to diseases or, in some cases, beneficial traits.
• Explore DNA repair mechanisms and their role in maintaining genetic integrity.

Recommended Common Core Standards:

• CCSS.ELA-Literacy.RST.9-10.3: Follow precisely a complex multistep procedure when performing technical tasks.
• CCSS.ELA-Literacy.RST.9-10.4: Determine the meaning of key terms and concepts in scientific texts.

Courses Perfect For:

• High School Biology
• Genetics Units
• AP Biology Supplement

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